The Ch/π Interaction: Evidence, Nature, and Consequences

ISBN-13: 9780471252900 / Angielski / Twarda / 1998 / 232 str.

Motohiro Nishio; Minoru Hirota; Yoji Umezawa

Opis

Molecules are held together by chemical bonds. The CH-( interactions deals with the interactions between two bonds, which contributes to the shape and reactivity of the molecule. This book presents an overview of the experimental basis, theoretical background, and nature of the CH-( Interactions. The CH-( Interaction refers to a weak attractive force that originally was inferred from structural data obtained by spectroscopy. The characteristics of this weak force are compared to those of other hydrogen bonds.

Spis treści

Evidence and Methods of Detection.

Quantum–Mechanical Treatment of CH– Interaction.

Comparison with Other Types of Weak Molecular Interactions.

Conformational Consequences.

Chiroptical Properties.

Selectivity in Organic Reactions.

Crystal Structures of Clathrates.

Inclusion Compounds.

Interligand Interactions in Coordination Chemistry.

Specific Interactions in Protein Structures.

Summary and Prospects.

Index.

O autorze

MOTOHIRO NISHIO is Professor in the Department of Materials Science at Chiba University in Chiba, Japan. MINORU HIROTA is Professor in the Department of Applied Chemistry at Yokohama National University in Yokohama, Japan. YOJI UMEZAWA is Vice Director in the Department of Medicinal Chemistry at the Institute of Microbial Chemistry in Tokyo, Japan.

Blurb

A systematic exploration of the fascinating area of CH/p interaction–from the frontier of chemical research

The CH/p bond may be the weakest of the hydrogen bonds, but it has been found to play important roles in the physical, chemical, and biological properties of a variety of substances. This book offers a complete overview of the experimental basis, theoretical background, and nature of the CH/p interaction to facilitate a clearer common understanding of the interaction between CH bonds and p–systems. Featured topics include:
∗ Evidence and methods of detection
∗ Quantum chemical treatment of CH/p interaction
∗ Comparison with other types of weak molecular interactions
∗ Conformational consequences
∗ Chiroptical properties
∗ Selectivity in organic reactions
∗ Crystal structures of clathrates
∗ Inclusion compounds
∗ Interligand interactions in coordination chemistry
∗ Specific interactions in protein structures
∗ Prospects and possibilities for use in biochemistry and materials science

The CH/p Interaction makes an important contribution to the understanding of weak intermolecular forces and their potential value to the biochemical and pharmaceutical sciences. It will be welcomed by physical and synthetic organic chemists; structural chemists; and pharmaceutical and biochemists.