The Brain as a Drug Target: Volume 98

ISBN-13: 9780123855060 / Angielski / Twarda / 2011 / 468 str.

Rahman A R

Opis

The brain is protected by the blood-brain barrier and this barrier prevents many drugs from entering the brain. This volume discusses various drug delivery and targeting strategies that are being developed to enhance the transport and distribution of drugs into the brain.

* Discusses new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields

Recenzje

PRAISE FOR THE SERIES "Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal

Spis treści

1. Monoamine Transporters: Vulnerable and Vital Doorkeepers Zhicheng Lin, Juan J. Canales, Thröstur Björgvinsson, Morgane M. Thomsen, Hong Qu, Qing-Rong Liu, Gonzalo E. Torres, and S. Barak Caine 2. Therapeutic Targets in Alzheimer Disease and Related Tauopathies Christopher P. Corbo and Alejandra del C. Alonso 3. Therapeutic Targets for Neuroprotection and/or Enhancement of Functional Recovery Following Traumatic Brain Injury Matthew L. Kelso and James R. Pauly 4. Insulin, Synaptic Function, and Opportunities for Neuroprotection John G. Mielke and Yu-Tian Wang 5. Molecular Alterations in Glioblastoma: Potential Targets for Immunotherapy Azizul Haque, Naren L. Banik, and Swapan K. Ray 6. Molecular Signaling and Translational Significance of the Corticotropin Releasing Factor System Patrick J. Ronan, and Cliff H. Summers 7. Molecular targets of alcohol action: translational research for pharmacotherapy development and screening Giorgio Gorini, Richard L. Bell, and R. Dayne Mayfield 8. Brain Nicotinic Receptors as Emerging Targets for Drug Addiction: Neurobiology to Translational Research Shafiqur Rahman 9. Glutamatergic Neuroplasticity in Cocaine Addiction Joachim D. Uys and Kathryn J. Reissner 10. Role of the serotonergic system in alcohol dependence: from animal models to clinics Verity R. Johnson, Jason M. Weedman, Youssef Sari

O autorze

Shafiqur Rahman, Ph.D. is Professor of Pharmacology in the Department of Pharmaceutical Sciences at South Dakota State University (SDSU) in Brookings, USA. He received his Ph.D. in Neuropharmacology from the Memorial University of Newfoundland, Canada. Dr. Rahman completed his post-doctoral fellowship in the Department of Psychiatry from Indiana University School of Medicine in Indianapolis in USA. Prior to joining SDSU, he worked as research scientist and faculty at the University of Kentucky in Lexington, USA and the University of Toronto, Canada. Dr. Rahman's research focus is drug discovery in neuropharmacology, i.e. the development of novel therapeutic candidates for the treatment of drug addiction and neuropsychiatric disorders. His research and scholarship has resulted in over 125 publications and 11 edited books/book chapters. Dr. Rahman served as editor, editorial board member and reviewer for numerous Scientific Journals and review panels related to drug addiction, neuropharmacology, and drug discovery research. Dr. Rahman is also a member of several professional societies or organizations, including Society for Neuroscience, American Society for Experimental Neurotherapeutics, and American Society for Pharmacology and Experimental Therapeutics.