The Big Book on Small Heat Shock Proteins

ISBN-13: 9783319358079 / Angielski / Miękka / 2016 / 610 str.

Robert M. Tanguay; Lawrence E. Hightower

Opis

Based upon a workshop entitled "The Small HSP World" held in Quebec 2-5 October 2014. These colleagues include Arrigo, Benesch, Benjamin, Buchner-Haslbeck-Weinkauf, Benndorf, Boelens, Carra, Chang, Currie, Ecroyd, Emanuelsson, Fu, Garrido, Golenhofen, Gusev, Hightower, Kampinga, Lavoie, MacRae, Quinlan, Tanguay, Vierling, Vigh, Weeks and Wu.

Spis treści

Foreword (tanguay- Hightower)

Section 1 : General Introduction

1 Kampinga Harm H, de Boer Romy, Beerstra Nico
The multicolored world of the HSPB family

2 Arrigo André Patrick, Ducarouge Benjamin, Lavial Frice, Gibert Benjamin
Immense implications associated to small stress expression : impacts on human pathologies

Section 2 : Structure-function

3 Hochberg Georg K A, Benecht Justin L P
"Dynamics-function relationship sof the small Heat shock Proteins

4 Fu Xinmiao
Insights into how small heat shock proteins bind a great diversity of substrate proteins : a super transformer model

5 Santhanagopalan Indu, Basha Eman, Ballard Keith N, Bopp Nathan E, Vierling Elizabeth
Model chaperones : small heat shock proteins from plants

6 Haslbeck Martin, Weinkauf Sevil, Buchner Johannes
Regulation of the chaperone function of small Hsps

7 Ecroyd, Heath
Redefining the chaperone mechanism of sHsps: not just holdase chaperones

8 Heirbaut Michelle, Strelkov Sergei V, Weeks Stephen
Everything but the ACD, functional conservation of the non-conserved regions in sHSPs

9 Sudnitsyna Maria V, Sluchanko Nikolai N, Guzev Nikolai B
HspB6 (Hsp20) as a versatile molecular regulator

10 Bernfur K, Rutsdottir G, Emanuellsson, Cthe chloroplast-localized plant sHSP in Arabidopsis thaliana- role of its oligomeric conformation and its translocation into membranes

Section 3: SHsps in the clinic

11 Mitzelfelt Kathie A, Benjamin Ivor J
Multifunctional roles of crystallin in skeletal and cardiac muscle homeostasis and disease

12 Boehlens Wilbert (Neijmegen)
Role of small heat shock protein HspB5 in cancer

13 Bellaye Pierre-Simon, Burgy Olivier, Colas julien, Causse Sébastien, Garrido Carmen, Bonniaud Philippe
Small heat shock proteins and fibrosis14 Rioux Danielle A, Murphy Kathleen, Esser Michael J, Currie R William
Neurodegenerative diseases, sex differences and the 27 kDa heat shock protein in the nervous system

15 Golenhofen Nokola, Bartelt-Kirbach Britta
HspB5/B-crystallin in the brain

16 Guo Huan, Wu Tangchun
Small HSP variants and diseases

Section 4: SHsps cellular and molecular mechanisms of action

17 Perng MD, Quinlan Roy A
The dynamic duo of small heat proteins and Ifs maintain cell homeostasis, resist cellular stress and enable evolution in cells and tissues

18 Guilbert Solenn M, Varlet Alice-Anais, Fuchs Margit, Lambert Herman, Landry Jacques, Lavoie Josée N
Regulation of actin-based structure dynamics by HspB proteins and partners

19 Doshi Bindi, Hightower Lawrence E, Heat shock alters keratocyte movement and morphology: exploring a role for HSP17 (HSPB1)

20 Benndorf, Rainer, Jungblut Peter R
Reconsidering Old Data: Non-Canonical HspB1 Species and the Enigma of the Cytoskeletal Function of HspB1

21 Poletti Angelo, Carra Serena
Role of HSPB8 in the proteases network: from protein synthesis to protein degradation and beyond

22 Chang Zengyi
Understanding what small heat shock proteins do for bacterial cells

23 Toth Melinda E , Santha Miklos, Penke Botond, Laszlo Vigh
How to stabilize both the proteins and the membranes : diverse effects of sHsps in neuroprotection

24 MacRae, Tom
Small Heat Shock Proteins and Diapause in the Crustacean, Artemia franciscana

25 Tanguay Robert M, Morrow Geneviève
Drosophila small heat shock proteins : an update on their features and functions

Index

Blurb

Based upon a workshop entitled “The Small HSP World” held in Québec 2-5 October 2014. Twenty-five scientists provided chapters for the book. The chapters are from the best scientists currently working in this field.  These colleagues include Arrigo, Benesch, Benjamin, Buchner-Haslbeck-Weinkauf, Benndorf, Boelens, Carra, Chang, Currie, Ecroyd, Emanuelsson, Fu, Garrido, Golenhofen, Gusev, Hightower, Kampinga, Lavoie, MacRae, Quinlan, Tanguay, Vierling, Vigh, Weeks and Wu. Briefly, the book starts with the structure of small heat shock proteins, moving to their functions and finishing with their involvement in diseases. Although this is quite broad, the structural aspect will be the unifying theme of the book.