The Azide-Alkyne 1,3-dipolar Cycloaddition Click Chemistry

ISBN-13: 9783841661050 / Angielski / Miękka / 2018 / 84 str.

Zineb Tribak

Opis

My researches, being done focus on the synthesis of a new series of 5-Chloroisatin derivatives using N-alkylation reactions under the conditions of phase transfer catalysis (PTC) by various alkylating agents, as well as that 1,3-dipolar cycloaddition reactions involving azides as dipoles on the dipolarophiles prepared previously, the structures of the various compounds obtained were determined spectroscopically (1H NMR, 13C NMR). Quantum chemistry calculations were used to study the reaction mechanisms and to interpret experimental results using the DFT/B3LYP/6-31G method.

O autorze

Tribak, Zineb
I am Zineb Tribak, I recently completed a PhD in chemistry at the Faculty of Science and Technology of Fez, Sidi Mohammed Ben Abdellah University of Morocco, in July 2017 and it was titled: "Synthesis, electrochemical study and biological evaluation of new heterocyclic systems derived from 5-Chloroisatin".