Targeting Treatment of Soft Tissue Sarcomas

ISBN-13: 9781475779417 / Angielski / Miękka / 2013 / 184 str.

J. Verweij; H. M. Pinedo

Opis

- Discusses the latest drug treatments in the field - Gleevec arranged a bulk sale for this title - Written by leaders in the industry

Recenzje

"The management of soft tissue sarcomas remains a difficult challenge. However, significant advances have occurred in our understanding of the important signaling molecules in these diseases. Experts in the field discuss the critical therapeutic targets and relevant treatment strategies for these malignancies."
(Steven T. Rosen, M.D., Series Editor)

Spis treści

Targeted therapy: Ready for prime time?.- Volume-based radiotherapy targeting in soft tissue sarcoma.- Preoperative therapy for soft tissue sarcoma.- TNF-based isolated limb perfusion: A decade of experience with antivascular therapy in the management of locally advanced extremity soft tissue sarcomas.- Pitfalls in pathology of soft tissue sarcomas.- Molecular biology and cytogenetics of soft tissue sarcomas: Relevance for targeted therapies.- KIT and PDGF as targets.- Targeting mutant kinases in Gastrointestinal Stromal Tumors: A paradigm for molecular therapy of other sarcomas.- Targeting other abnormal signaling pathways in sarcoma: EGFR in synovial sarcomas, PPAR-? in liposarcomas.- Angiogenesis: a potential target for therapy of soft tissue sarcomas.