Systems Biology: Applications and Perspectives

ISBN-13: 9783540313380 / Angielski / Twarda / 2006 / 177 str.

Bringmann

Opis

This volume features contributions from participants of an ESRF Workshop on "Systems Biology" held in Berkeley, USA, in November 2005. Significant progress has been made in developing technologies that enable systems interrogations at a molecular level. Recent successes and challenges of applying systems level measurements to the different steps of drug discovery and development in the pharmaceutical industry are summarized.

Spis treści

RNAi Applications in Target Validation.- Does the Serum Peptidome Reveal Hemostatic Dysregulation?.- Systems Biology: New Paradigms for Cell Biology and Drug Design.- The Theory of Biological Robustness and Its Implication in Cancer.- Network Genomics.- A Plea for More Theory in Molecular Biology.- Applying a Causal Framework to System Modeling.- Can Cell Systems Biology Rescue Drug Discovery?.