Synthetic Studies on N-aryl-gamma-lactams

ISBN-13: 9783838370866 / Angielski / Miękka / 2010 / 164 str.

Haldar, Pranab

Opis

Due to growing number of bacterial strains acquiring resistance to the current arsenal of chemotherapeutic drugs, the search for novel anti bacterial agents continue to be a major area of research in many fronts.During the last decade,various groups have directed their efforts to synthesize various bioactive gamma-lactams. Modification of lactam ring has been playing a vital role in determining the bio-activities of these derivatives and so exploration of a novel methodology in a simple way is a pivotal focal point of research activity in bioorganic chemistry. Progress in the art of organic synthesis in the last decades has been achieved by marked advances in chemo-,regio-and stereoselective functional group transformations by using classical and newly developed reagents. The book entitled "Synthetic Studies on N-aryl- gamma-lactams" is an embodiment of research aimed at developing simple methodologies for selective functional group transformations of N-aryl- gamma-lactams and an effort towards the development of new synthetic strategies for conversion of N-aryl- gamma-lactams to substituted pyrrole and pyrroloquinoline derivatives.

O autorze

Pranab Haldar obtained his PhD from I.I.T,Kharagpur. After his postdoctoral research from UAB(USA),he joined DR Reddy s Laboratories Ltd(India)in 2008 as Sr. Scientist. His research interests focus on design,synthesis & process development of Active Pharmaceutical Ingredients. He received Young Scientist award from Indian Chemical Society.