Synthetic Sequences in Organic Chemistry

ISBN-13: 9781032502946 / Angielski

Jerome Zoeller

Opis

Drawing on the vast amount of experience the author has gained from working in industrial and university laboratories, this collection of excerpt reports contains essential details from literature relevant to the synthesis of compounds on a milligram to kilogram scale. The excerpts are composed using ChemDraw software and compiled in a Word document. A number of the compounds that have eluded efficient preparation in the past are now presented. Material which will improve any chemist's existing synthetic methodology can be found here. Each of the six chapters, with eighty excerpts, illustrates a novel application of syntheses selected from twenty first century literature.

Features:

This professional text describes many of the classical and contemporary methods of synthesis that have recently found great value in the preparation of needed target compounds in the required quantities.

Each example is extracted from a specific literature publication, which the user then would examine for details.

This user-friendly professional text provides enormous aid in designing synthetic sequences.

Appeals to a broad audience in both academic and industrial laboratories, basically any chemist in need of designing a synthetic sequence or just selecting a single reaction.

Author has a vast amount of experience gained from working in academic and industrial laboratories.

 

Spis treści

1. Non-Natural Oranic Compounds. 2. Structural Moieties and Functional Groups . 3. Natural Products. 4. Diversification and Simplification. 5. Name Reactions. 6. Variations on a Synthetic Sequence

O autorze

Jerome Zoeller graduated from Rensselaer Polytechnic Institute, USA, with a B.S. in Chemistry and began work at the Rohm & Haas Co. in applications and pro-cess development with acrylic polymers. Graduate study followed at the University of Texas, USA, with research concentration in physical organic chemistry. Upon completing the Ph.D. program, he went on for two years as a Postdoctoral Research Fellow in the use of organometallics in synthetic and structural studies. At the Southwest Foundation for Research and Education he developed preparative methods for cortisol analogs, and their use in affinity chromatography and primate brain research. In this decade he lectured at Trinity University, USA. A change in career occurred in which he studied Fuel Science at The Pennsylvania State University, USA. This specialty was pursued at Texas A&M University, USA, in the use of specialized oxidative transformations in studies of fossil fuel structure. Upon retirement he moved to a startup pharma company, Targacept Inc., for synthetic work on nicotinic acetylcholine esterase ligands of potential neurological activity. Upon moving to Texas, he was prompted to compile some of the synthetic sequences displayed in the twenty-first century literature, for this book.