Synthesis and characterization of Triazolo[4,3-c]pyrimidine library

ISBN-13: 9783659639852 / Angielski

Kalpesh Vilapara; Sagar Gami

Opis

A novel [1,2,4]triazolo[4,3-c]pyrimidine-8-carboxamide libraries were synthesized via oxidative cyclization of hydrazono-1,6-dihydropyrimidine-5-carboxamide intermediates by the application of Iodobenzenediacetate as a sole cyclizating agent. Here, we report one pot sequential strategy to generate corresponding triazolopyrimidines by condensation of preprepared -acylketene dithioacetals and arylamidines. Moreover, this process describes the application of presynthesized arylamidines which omits the transition metal catalyzed Suzuki-Miyaura cross coupling reaction hence signify the atom- and step-economic methodology.

O autorze

Vilapara, Dr. Kalpesh
Dr. Kalpesh VilaparaM.Sc., Ph.D. Chemistry,Saurashtra University,Rajkot-360005