Studies in Natural Products Chemistry: Volume 51

ISBN-13: 9780444639325 / Angielski / Twarda / 2016 / 552 str.

Atta-Ur-Rahman

Opis

Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. This series covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

• Focuses on the chemistry of bioactive natural products
• Contains contributions by leading authorities in the field
• Presents sources of new pharmacophores

Spis treści

1. Potentially Chemopreventive Triterpenoids and Other Secondary Metabolites From Plants and Fungi 2. Structural Diversity, Natural Sources and Pharmacological Potential of Naturally Occurring A-Seco-Triterpenoids 3. Kaurenoic Acid: A Diterpene With a Wide Range of Biological Activities 4. Review of Patents Based on Triterpene Glycosides of Sea Cucumbers 5. Bioactive Dietary Compounds Regulate Mitochondrial Apoptosis Signaling in Ambivalent Way to Function as Neuroprotective or Antitumor Agents 6. Dietary Carotenoids for Reduction of Cancer Risk 7. Dihydrochalcones: Occurrence in the Plant Kingdom, Chemistry and Biological Activities 8. Synthetic Advances in the Indane Natural Product Scaffolds as Drug Candidates: A Review 9. Garcinoic Acid: A Promising Bioactive Natural Product for Better Understanding the Physiological Functions of Tocopherol Metabolites 10. Antibiotics Derived From Marine Organisms: Their Chemistry and Biological Mode of Action

O autorze

Atta-ur-Rahman, Professor Emeritus, International Center for Chemical and Biological Sciences (H. E. J. Research Institute of Chemistry and Dr. Panjwani Center for Molecular Medicine and Drug Research), University of Karachi, Pakistan, was the Pakistan Federal Minister for Science and Technology (2000-2002), Federal Minister of Education (2002), and Chairman of the Higher Education Commission with the status of a Federal Minister from 2002-2008. He is a Fellow of the Royal Society of London (FRS) and an UNESCO Science Laureate. He is a leading scientist with more than 1283 publications in several fields of organic chemistry.