Studies in Natural Products Chemistry: Bioactive Natural Products (Part XIII) Volume 50

ISBN-13: 9780444637499 / Angielski / Twarda / 2016 / 434 str.

Atta-Ur-Rahman

Opis

Studies in Natural Products Chemistry: Bioactive Natural Products (Part XIII) is the latest in a series that covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to quickly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

• Focuses on the chemistry of bioactive natural products
• Contains contributions by leading authorities in the field
• Presents sources of new pharmacophores

Spis treści

Chapter 1. Synthesis and Structure-Activity Relations in Allylsulfide and Isothiocyanate Compounds From Garlic and Broccoli Against In Vitro Cancer Cell Growth

Chapter 2. Natural Products as Lead Protein Kinase C Modulators for Cancer Therapy

Chapter 3. Plant-Derived Prooxidants as Potential Anticancer Therapeutics

Chapter 4. Anticancer and Antineurodegenerative Effects of Ginsenosides

Chapter 5. Role of Phytochemicals in MAPK Signaling Pathway-Mediated Apoptosis: A Possible Strategy in Cancer Chemoprevention

Chapter 6. Natural Products as Cathepsin Inhibitors

Chapter 7. Endemic Plants of Italy and Their Peculiar Molecular Pattern

Chapter 8. From Natural Products to Drugs: Glyco- and Lipoglycopeptides, a New Generation of Potent Cell Wall Biosynthesis Inhibitors

Chapter 9. CH Bond Activation as a Powerful Tool in the Construction of Biologically Active Nitrogen-Containing Heterocycles

Chapter 10. Isolation, Bioactivity, and Synthesis of Nagelamides

Chapter 11. Nutraceuticals Neuroprotect Naturally: Alzheimer's disease, Parkinson's disease, Stroke and Major Depressive Disorder

Chapter 12. Nanotechnology-Based Approach for Enhanced Bioavailability and Stability of Tea Polyphenols-A Review

O autorze

Atta-ur-Rahman, Professor Emeritus, International Center for Chemical and Biological Sciences (H. E. J. Research Institute of Chemistry and Dr. Panjwani Center for Molecular Medicine and Drug Research), University of Karachi, Pakistan, was the Pakistan Federal Minister for Science and Technology (2000-2002), Federal Minister of Education (2002), and Chairman of the Higher Education Commission with the status of a Federal Minister from 2002-2008. He is a Fellow of the Royal Society of London (FRS) and an UNESCO Science Laureate. He is a leading scientist with more than 1283 publications in several fields of organic chemistry.