Studies in Natural Products Chemistry: Bioactive Natural Products (Part P) Volume 36

ISBN-13: 9780444538369 / Angielski / Twarda / 2012 / 415 str.

Atta-Ur Rahman

Opis

Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, and then determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry. The series also covers the synthesis or testing and recording of the medicinal properties of natural products. "There is a good mix of chemistry, structure elucidation, synthesis, and biology in the various chapters, thereby appealing to a diverse readership. The diagrams are clear and the writing excellent. In summary, this is another excellent volume in a very valuable series on natural products for which Professor Atta-ur-Rahman is to be congratulated...... an important and essential asset for those libraries supporting the efforts of natural product research groups." Geoffrey A. Cordell, University of Illinois, Chicago, USA, PHYTOCHEMISTRY, Vol.65, 2004

• Describes the chemistry of bioactive natural products
• Contains contributions by leading authorities in the field
• A valuable source for researchers and engineers working in natural product and medicinal chemistry

Spis treści

Preface
1. Isolation, Biological activities and Synthesis of the Natural Casuarines
2. The Acylpolyamines from Spider Venoms 
3. Deep-Sea Hydrothermal Vents as a New Source of Drug Discovery
4. Marine Cyanobacteria: A Treasure Trove of Bioactive Secondary Metabolites for Drug Discovery
5. Novel Bioactive Peptides from Cyanobacteria: Functional, Biochemical and Biomedical Significance
6. Bioactive Marine Prenylated Quinones/Quinols
7. Chlorosulfolipids
8. Diversity and Ecological Significance of Fungal Endophyte Natural Products
9. Flavonoids as Anti-Inflammatory and Analgesic Drugs: Mechanisms of Action and Perspectives in the Development of Pharmaceutical Forms
10. Antileishmanial Natural Products from Plants
Subject Index

O autorze

Atta-ur-Rahman, Professor Emeritus, International Center for Chemical and Biological Sciences (H. E. J. Research Institute of Chemistry and Dr. Panjwani Center for Molecular Medicine and Drug Research), University of Karachi, Pakistan, was the Pakistan Federal Minister for Science and Technology (2000-2002), Federal Minister of Education (2002), and Chairman of the Higher Education Commission with the status of a Federal Minister from 2002-2008. He is a Fellow of the Royal Society of London (FRS) and an UNESCO Science Laureate. He is a leading scientist with more than 1283 publications in several fields of organic chemistry.