Studies On Imidazopyrimidine Derivatives

ISBN-13: 9786200266293 / Angielski

Kalpesh Vilapara; Sagar Gami; Shobhna Gadara

Opis

Synthetic studies of fused pyrimidine have been reported extensively because of their structural diversity and association with a wide spectrum of biological activity. It has been observed over the years that poly substituted pyrimido[1,2-a]benzimidazoles possess a wide spectrum of biological activities and they are structurally related to natural purine bases. With this background we have prepared a library of imidazopyrimidine analogues by one pot Biginelly type multi-component reaction. The process has several advantages like neat reaction and easy workup and purification steps. All the synthesized compounds were evaluated for their antimicrobial activity. The investigation of antimicrobial and anti-fungal screening data revealed that all the tested compounds showed moderate to significant activity.

O autorze

Vilapara, Kalpesh
Dr. Kalpesh Vilapara, Dr. Sagar Gami and Shobhna Gadara trio author are actively engaged in the field of Bio-active hetero-cyclic synthesis as well as a researcher also involved in natural product and green chemistry research.