Stress and Inflammation in Disorders: Volume 108

ISBN-13: 9780128123881 / Angielski / Twarda / 2017 / 272 str.

Rossen Donev

Opis

Stress and Inflammation in Disorders, Volume 108, the newest volume in this ongoing series, brings forth new information on protocols and analysis of proteins. This volume covers the latest on Oxidative Stress: Love and Hate History in the Central Nervous System, Neuroinflammation in Alzheimer's Disease: The Preventive and Therapeutic Potential of Polyphenolic Nutraceuticals, Inflammation in Epileptic Encephalopathies, A Computational Approach to Identify the Biophysical and Structural Aspect of Methylenetetrahydrofolate Reductase (MTHFR) Mutations (A222V, E429A and R594Q) Leading to Schizophrenia, and Analyzing the Effect of V66M Mutation in BDNF in Causing MOOD Disorders- A Computational Approach. Each release in the Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

• Provides cutting-edge developments in protein chemistry and structural biology
• Features new information about protocols and analysis of proteins
• Contains chapters written by authorities in their respective fields
• Targeted to a wide audience of researchers, specialists, and students

Spis treści

1. Oxidative Stress: Love and Hate History in Central Nervous System G.G Ortiz, F.P.P. Moisés, M. Mireles-Ramírez, L.J. Flores-Alvarado, H. González-Usigli, V.J Sánchez-González, A.L Sánchez-López, L. Sánchez-Romero, E.I Díaz-Barba, J.F. Santoscoy-Gutiérrez and P. Rivero-Moragrega 2. Neuroinflammation in Alzheimer's Disease: The Preventive and Therapeutic Potential of Polyphenolic Nutraceuticals Y. Sawikr, N.S. Yarla, I. Peluso, M.A. Kamal, G. Aliev and A. Bishayee 3. Inflammation in Epileptic Encephalopathies O. Shandra, S.L. Moshé and A.S. Galanopoulou 4. Analyzing the Effect of V66M Mutation in BDNF in Causing MOOD Disorders- A Computational Approach P. Sneha, D. Thirumal Kumar, Sugandhi Saini, Kreeti Kajal, R. Magesh , R. Siva and C. George Priya Doss 5. A Computational Approach to Identify the Biophysical and Structural Aspect of Methylenetetrahydrofolate Reductase (MTHFR) Mutations (A222V, E429A and R594Q) Leading to Schizophrenia H. Tanwar, P. Sneha, D. Thirumal Kumar, R. Siva, C.E.J. Walter and C. George Priya Doss 6. Stress-Induced  NLRP3-Inflammasome in Human Diseases E. Alcocer-Gómez, B. Castejón-Vega and M.D. Cordero 7. Stress-Adaptive Response in Ovarian Cancer Drug Resistance: Role of TRAP1 in Oxidative Metabolism-Driven Inflammation M.R. Amoroso, D.S Matassa, I. Agliarulo, R. Avolio, F. Maddalena, V. Condelli, M. Landriscina and F. Esposito 8. Molecular Targets of Ascochlorin and its Derivatives for Cancer Therapy J.M.-W. Chua, B.Y.-J. Chua, S. Mishra, X. Dai, J. Magae, S.-C. Ng, A.P Kumar and G. Sethi 9. Cardiokines as Modulators of Stress-Induced Cardiac Disorders A. Planavila, J. Fernández-Solà and F. Villarroya

O autorze

Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2007 he was awarded a New Investigator Grant Award from the Medical Research Council (UK) to establish himself as an independent Principle Investigator. In 2010 Dr. Donev was appointed Senior Lecturer at Swansea University. In 2016 Dr. Donev joined MicroPharm Ltd (UK) where currently he is Head of Research. He has published more than 60 research papers, chaired scientific meetings and given invited plenary talks. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals. His research interests include signaling pathways involved in neuropsychiatric disorders and tumor escape from the immune system, and development of therapeutic strategies for their treatment. More recently he has focused on development of immunotherapeutics for non-systemic applications.