Strategies and Solutions to Advanced Organic Reaction Mechanisms: A New Perspective on McKillop's Problems

ISBN-13: 9780128128237 / Angielski / Miękka / 2019 / 884 str.

Andrei Hent; John Andraos

Opis

Strategies and Solutions to Advanced Organic Reaction Mechanisms: A New Perspective on McKillop's Problems builds upon Alexander (Sandy) McKillop's popular text, Solutions to McKillop's Advanced Problems in Organic Reaction Mechanisms, providing a unified methodological approach to dealing with problems of organic reaction mechanism. This unique book begins with three brief introductory chapters outlining the logic, experimental insight and problem-solving strategy approaches available when dealing with problems of organic reaction mechanism. These valuable methods emphasize a structured and widely applicable approach relevant for both students and experts in the field. From there, this book provides detailed and complete solutions to all 300 advanced problems originally posed by Dr. McKillop in his landmark work, Advanced Problems in Organic Reaction Mechanisms, published by Elsevier imprint Pergamon in 1997. With each solution, the authors apply their generalized approach for problems in organic reaction mechanisms over and over, showcasing all possible variations on the theme and helping the interested reader solidify his or her understanding of the underlying logic of organic chemistry. In providing worked examples to the many interesting case reactions and syntheses originally selected by Dr. McKillop, the authors go on to outline synthesis strategy; provide green metrics analysis where appropriate and potentially useful; highlight additional resources on novel research; and analyze identified errors and areas for further research. The book thus provides an invaluable guide and resource for understanding organic chemistry through pattern recognition rather than memorization. By using the methods described, advanced students and researchers alike will be able to tackle problems in organic reaction mechanism, from the simple and straight forward to the advanced.

• Provides strategic methods for solving advanced mechanistic problems and applies those techniques to all 300 problems from the original publication
• Replaces reliance on memorization with the understanding brought by pattern recognition to new problems
• Supplements worked examples with synthesis strategy, green metrics analysis and novel research, where available, to help advanced students and researchers in choosing their next research project

Spis treści

1. The Logic of Organic Reaction Mechanism
2. Experimental Tools
3. Problem Solving Strategy
4. Detailed Solutions