Stereoselectivity in Synthesis

ISBN-13: 9780471329220 / Angielski / Twarda / 1999 / 352 str.

Tse-Lok Ho

Opis

Many chemicals are found in "right-" and "left-handed" forms that may react differently in the body. In planning a synthesis, chemists must know how to select the best method for making the preferred form of a chemical. This book shows how to choose the best method for a given synthesis. It provides readers with a thorough understanding of stereoselectivity in organic and medicinal chemistry as well as the pharmaceutical, agricultural, and food industries.

Recenzje

"...research workers in this field will either wish to purchase this book or to have ready access to a copy" (Applied Organometallic Chemistry, Vol 15, 2001)

Spis treści

Some Fundamental Concepts.

1,2–Stereoinduction.

1,3–Stereoinduction.

Stereoinduction at Long Distances.

Group Directed Reactions and Chelation Effects.

Conformational Effects.

Topographical and Template Effects.

Steric, Electrostatic, and Stereoelectronic Effects.

Thermodynamic Control and Kinetic Trapping.

Index.

O autorze

Tse-Lok Ho is Professor of Organic Chemistry at National Chiao Tung University in Taiwan. His research interests are in organic synthesis, including total synthesis of natural products and methodology. He has written 12 books, including, most recently, Stereoselectivity in Synthesis, available from Wiley. Dr. Ho holds degrees from National Taiwan University and the University of New Brunswick, Canada.