Sepsis and Organ Dysfunction: The Challenge Continues

ISBN-13: 9788847000964 / Angielski / Miękka / 1999 / 168 str.

A. E. Baue; G. Berlot; A. Gullo

Opis

Progression of the sepsis-MODS syndrome is tied to: the severity and location of the lesion; the patient's age; the remaining functional reserve; and the presence of mediatory which may be stimulatory, inhibitory or both. This overview is aimed at anaesthesiologists and doctors.

Spis treści

Sepsis and Organ Dysfunction. The Challenge Continues.- Oxygen Transport in Sepsis.- Biochemical Regulation of the Microcirculation.- Oxygen Supply and Consumption in Tissues.- Ischaemia-Reperfusion in Sepsis.- Mechanism of Oxygen Extraction Defect in Septic Shock.- Organ Dysfunction and Biohumoral Mismatch in Sepsis.- Gut Perfusion in Sepsis and Shock.- Pathophysiology of Encephalopathy.- Lung Dysfunction in the Early Phase of Sepsis.- The Kidney in Sepsis.- Pathophysiology of Liver Dysfunction in Sepsis.- Inflammatory Cells in Septic Shock.- Sepsis Trial.- Revised Terminology on Sepsis.- The Epidemiology and Outcome of Patients with Sepsis: Clear as Mud.- Are there Useful New Markers of Sepsis?.- A Paradigm Shift: The Bidirectional Effect of Inflammation on Bacterial Growth.- Is the Dosing and Timing of the Intervention Adequate?.- Clinical Trials of Mediator-Targeted Therapy in Sepsis.