SIGMA Proteins: Evolution of the Concept of SIGMA Receptors

ISBN-13: 9783319881164 / Angielski / Miękka / 2018 / 330 str.

Felix J. Kim; Gavril W. Pasternak

Spis treści

Preface.- Historical perspective and background - including Sigma protein subtypes and ligand selectivity.- Sigma imaging agents.- Medicinal chemistry.- 3-dimensional homology models of Sigma1.- Neuronal plasticity and ion channels.- Opioid receptors and other GPCR.- Cancer.- Neurodegenerative diseases.- Pain.- Cognition, learning, neurological disorders.- Drug abuse and addiction.- Alcohol Abuse.- Stroke and neuroprotection.

O autorze

Felix J Kim PhD, Drexel University, College of Medicine, Pharmacology and Physiology, 

Philadelphia, USA

Gavril Pasternak MD Ph., Memorial Sloan-Kettering Cancer Center, Anne Burnett Tandy Chair in Neurology, Molec Pharmacology and Chemistry, New York, USA