Reproducibility in Biomedical Research: Epistemological and Statistical Problems and the Future

ISBN-13: 9780443138294 / Angielski / Miękka / 2024 / 420 str.

Department of Medicine (Ne MD (Emeritus Professor Erwin B.

Spis treści

1. Introduction
2. The Problem of Irreproducibility
3. Validity of Biomedical Science, Reproducibility, and Irreproducibility
4. The Logic of Certainty versus the Logic of Discovery
5. The Logic of Probability and Statistics
6. Causation, Process Metaphor, and Reductionism
7. Case Studies in Clinical Biomedical Research 8. Case Studies in Basic Biomedical Research
9. Case Studies in Computational Biomedical Research
10. Case Studies in Machine Learning Artificial Intelligence (AI)
11. Reproducibility of translation from biomedical research to clinical care
12. Chaotic and Complex Systems, Statistics, and Far-from-Equilibrium Thermodynamics
13. The Nature of the Fundamental Challenges to Reproducibility in any Knowledge Discipline
14. Epilogue
15. Appendix: Types of lack of reproducibilityility