Regulation of CoQ10 and/or lipoic acid

ISBN-13: 9786200539922 / Angielski / Miękka / 2020 / 268 str.

Mona Fathy; Sanaa Wahba; Mohamed Heibashy

Opis

Obesity is a serious health problem which has become prevalent in developed countries in recent years. Physiologically, it results from an imbalance between energy intake and energy expenditure and is characterized by increased fat accumulation in adipose tissue and elevated lipid concentrations in blood. Visceral fat mass is more closely correlated with obesity-associated pathology than overall adiposity.Hypertension is considered one of the prevalent risk factors for coronary heart disease, cardiovascular disease, ischemic heart disease and cardiac failure in which systolic blood pressure and diastolic blood pressure are increasing compared to normal level. Hypertension leads to endothelial dysfunction and sebsequently damage this layer.The present study aimed to investigate the effects of P-407 and sodium chloride induced obesity and hypertension in male albino rats and, therapeutic effects of administration of CoQ10 and/or ALA as a rare element with antioxidant properties in ameliorating induced damage on heart tissue and some biochemical parameters.

O autorze

Fathy, Mona
Mona Fathy, graduated from the Faculty of Science (Faculty of Women for Arts, science and Education) at Ain Shams University in 2015 and worked as a assistant lecturer at Ain Shams University, Cairo, Egypt. She has got a master's degree in December 2019 with a specialization in histology and histochemistry. Is seeking to progress to PhD degree.