Reductions by the Alumino- And Borohydrides in Organic Synthesis

ISBN-13: 9780471190363 / Angielski / Twarda / 1997 / 224 str.

Jacqueline Seyden-Penne; J. Seyden-Penne

Opis

This volume discusses alumino- and borohydrides, which are reducing agents used in organic synthesis. It serves as a guide to choosing reagents for reductions as part of organic synthesis. The volume also contains data of these reagents which include properties, reactivity and optimal condition.

Spis treści

Description and Characteristics of the Main Reagents.

Cleavage of the Carbon–Heteroatom Single Bond.

Reduction of Double Bonds.

Reduction of Triple Bonds.

Other Derivatives.

Synoptic Tables.

References.

Index.

O autorze

Jacqueline Seyden–Penne, PhD, is Emeritus Director of Research at CNRS. From 1972 to 1991, she taught postgraduate organic chemistry at Orsay University in Paris, and she served as the head of a CNRS Research Unit at Orsay from 1983 to 1991. She has published more than 200 research papers in international journals and was scientific editor of the Bulletin de la Société Chimique de France and the Journal of Chemical Research. Dr. Seyden–Penne is an acknowledged international authority on carbanions and selective stereochemical methods in organic synthesis.

Blurb

A complete guide to selection and use of the best reagents for a wide range of transformations

This book is the updated and expanded Second Edition of Jacqueline Seyden–Penne′s practical guide to selection of reducing reagents in organic synthesis. It is an indispensable working resource for organic synthetic chemists–the only reference focusing exclusively on aluminohydrides and borohydrides and their derivatives.

Simple to use, it is organized according to specific reductions so that chemists can more easily match the best reagent to a given transformation. Throughout, Dr. Seyden–Penne emphasizes four crucial categories: compatibility, possibilities for partial reduction, the regio– and stereoselectivity of reductions that are altered or controlled by neighboring groups, and asymmetric reductions.

Extremely well–referenced, Reductions by the Alumino– and Borohydrides in Organic Synthesis provides the most up–to–date, detailed coverage of:
∗ Successful techniques for performing highly selective reductions
∗ Chemo–, regio–, stereo–, and enantioselective reductions of both simple and complex compounds
∗ Best methods for obtaining the main functional groups by hydridereduction, provided in quick–reference tabular form
∗ New and more selective reagents developed within the last five years
∗ Experimental conditions, including solvent and temperature, and yields for most cases described.