Pyrazolo[3,4-d]pyrimidines and their polycyclic derivatives

ISBN-13: 9783659872334 / Rosyjski / Miękka / 2016 / 60 str.

Mihail Bratenko; Mihail Vovk; Anton Bentia

Opis

Pyrazolo[3,4-d]pyrimidines are substances that found applications in medical practice (allopurinol) and have a number of biological activities: antimicrobial, antiinflammatory, anticancer, etc. Methods of synthesis, including both variants of pyrazole nucleus annulation by pyrimidine ring and pyrimidine nucleus by pyrazole ring, chemical and biological properties of pyrazolo[3,4-d]pyrimidine, and methods of their synthetic usage for the construction of synthetic polycyclic systems have been analyzed and generalized in the review.

O autorze

Doctor of chemical Sciences, professor, Head of the department of the medical and pharmaceutical chemistry of Bukovinian State Medical University (c.Chernivtsi), area research interests -chemistry pyrazole, bioorganic chemistry.