Public Health and Toxicology Issues in Drug Research, Volume 2: Toxicity and Toxicodynamics

ISBN-13: 9780443158421 / Miękka / 2024 / 650 str.

Spis treści

1. Biomarkers of Diseases
2. Connecting Biotransformation with toxicity
3. Implication of sex differences in toxicology
4. Design of toxicokinetic studies
5. Use of Toxicokinetic Data in Preclinical Safety Assessment
6. Drug-Induced Oxidative Stress as a Mechanism of Toxicity
7. Drug-induced nephrotoxicity and its biomarkers
8. Drug-induced Neurotoxicity
9. Drug-induced Cardiotoxicity
10. Drug-induced Immune toxicity
11. Drug-Induced Photosensitivity
12. Toxic effects of cancer therapies
13. High-content screening in toxicology
14. High-throughput screening in toxicity assessment
15. Population Pharmacokinetics/Toxicokinetics
16. Quantitative Extrapolation Interspecies Scaling/Low Dose Extrapolation
17. Toxicity and toxicodynamics of Cryoprotectant used in pharmaceutical products
18. Thermal processing and food-related toxicants
19. Toxicity of dental material
20. Toxicity of local anaesthetics
21. Clinical toxicity of antibody drug conjugates
22. Cumulative toxicity of herbal drugs
23. Radiotherapy toxicity
24. Toxicities and toxicodynamics of topical ophthalmic anesthetics
25. Toxicity of nanomaterials
26. Bioaccumulation of pharmaceutical and personal care products
27. Pesticides and Parkinson's disease--is there a link?
28. Chemo preventive role of dietary phytochemicals
29. Nutritional supplements as a potential source of positive doping
30. Ethical, Legal, Societal and Professional issues in Toxicology