Protein Arrays, Biochips and Proteomics: The Next Phase of Genomic Discovery

ISBN-13: 9780824743123 / Angielski / Twarda / 2003 / 422 str.

Joanna S. Albala; Ian Humphery-Smith;Humphery-Smith Ian

Opis

From disease marker identification to accelerated drug development, Protein Arrays, Biochips, and Proteomics offers a detailed overview of current and emerging trends in the field of array-based proteomics. This reference focuses on innovations in protein microarrays and biochips, mass spectrometry, high-throughput protein expression, protein-protein interactions, structural proteomics, and the proteomic marketplace for comprehensive understanding of past, present, and future proteomic research. Offering an abundance of figures and charts, the book compiles a wide variety of technologies and applications ranging from functionalized chip surfaces to strategies for protein expression.

Spis treści

Protein biochips and array-based proteomics; ultrasensitive microarray-based ligand assay technology; practical approaches to protein microarrays; proteomics biochips - powerful new tools to unravel the complexity of proteomics; functional surfacesfor protein microarrays - state of the art, challenges and perspectives; high-throughput protein expression, purification and characterization technologies; protein libraries for proteomics; protein profiling - proteomes and subproteomes; shotgunproteomics and its applications to yeast; forward and reverse proteomics - it takes two (or more) to tango; dynamic visualization of expressed gene networks; high-throughput structural biology and proteomics; the integration of proteomic, genechip and DNAsequence data; the proteomics market.

O autorze

Joanna S. Albala, Ian Humphery-Smith