Progress in Medicinal Chemistry: Volume 49

ISBN-13: 9780123812926 / Angielski / Twarda / 2010 / 192 str.

G. Lawton; D. R. Witty

Opis

Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems.

• Presents the latest research in the field of drug discovery
• Publishes on a twice yearly basis to bring you the most innovative updates in medicinal chemistry
• Available as an online resource via ScienceDirect

Spis treści

1. The Journey to the Discovery of Boceprevir: an NS3-NS4 HCV Protease Inhibitor for the Treatment of Chronic Hepatitis C - Kevin Chen & George Njoroge
2. A Decade of Progress in the Discovery and Development of 'Atypical' Antipsychotics - Gregor Madconald & Jose Manuel Bartolome
3. Structural Trends amongst Second Generation Voltage-Gated Sodium Channel Blockers - Mark Kemp
4. Computational Analysis of Structure-Activity Relationships - Peter Gedeck, Peter Ertl & Christian Kramer