ISBN-13: 9780306463051 / Angielski / Twarda / 1999 / 256 str.
This series is dedicated to serve as a collection of reviews on various aspects of the cell division cycle, with special emphasis in less studied aspects. This fourth volume starts with a review of RAS pathways and how they impinge on the cell cycle (chapter 1). In chapter 2, an overview is presented of the links between cell anchorage - cytoskeleton and cell cycle progression. A model of the G1 control in mammalian cells is provided in chapter 3. The role of histone acetylation and cell cycle control is described in chapter 4. Then follow a few reviews dedicated to specific cell cycle regulators: the 14-3-3 protein (chapter 5), the cdc7/Dbf4 protein kinase (chapter 6), the two products of the p16/CDKN2A locus and their link with Rb and p53 (chapter 7), the Pho85 cyclin-dependent kinases in yeast (chapter 9), the cdc25 phosphatase (chapter 10), RCC1 and ran (chapter 13). The intriguing phosphorylation-dependent prolyl-isomerization process and its function in cell cycle regulation are reviewed in chapter 8.