Problems in Organic Structure Determination: A Practical Approach to NMR Spectroscopy

ISBN-13: 9781498719629 / Angielski / Miękka / 2015 / 755 str.

Roger G. Linington; Philip G. Williams; John B. MacMillan

Opis

At a point where most introductory organic chemistry texts end, this problems-based workbook picks up the thread to lead students through a graduated set of 120 problems. With extensive detailed spectral data, it contains a variety of problems designed by renowned authors to develop proficiency in organic structure determination. This workbook leads you from basic problems encountered in introductory organic chemistry textbooks to highly complex natural product-based problems. It presents a concept-based learning platform, introducing key concepts sequentially and reinforcing them with problems that exemplify the complexities and underlying principles that govern each concept. The book is organized in such a way that allows you to work through the problems in order or in selections according to your experience and desired area of mastery. It also provides access to raw data files online that can be downloaded and used for data manipulation using freeware or commercial software. With its problem-centered approach, integrated use of online and digital resources, and appendices that include notes and hints, Problems in Organic Structure Determination: A Practical Approach to NMR Spectroscopy is an outstanding resource for training students and professionals in structure determination.

Spis treści

Structure Confirmation for Simple Molecules. Structure Confirmation for Complex Molecules. Determination of Unknown Structures for Simple Molecules. Determination of Unknown Structures for Complex Molecules. Complex Unknown Natural Product Structure Determination. Appendices.

O autorze

Roger G. Linington, PhD, is a Tier II Canada Research Chair in Chemical Biology and High-Throughput Screening in the Department of Chemistry at Simon Fraser University, Burnaby, British Columbia, Canada. He earned his PhD from the University of British Columbia. His postdoctoral research was a joint appointment between the University of California San Diego and the Smithsonian Tropical Research Institute, which gave him the opportunity to participate in an international neglected disease drug discovery program in Panama City, Panama. He was also a faculty member in the Department of Chemistry and Biochemistry at the University of California Santa Cruz for eight years.

Philip G. Williams, PhD, caught the spectroscopy bug as a summer research student at the University of Calgary while working on a series of alkaloids from African plants. He earned his PhD at the University of Hawaii at Manoa. He did his postdoctoral work at the Scripps Institution of Oceanography in San Diego on microbial natural products before returning to the University of Hawaii at Manoa as a faculty member. His research interests are natural products and their applications in the fields of cancer and neurological diseases.

John B. MacMillan, PhD, is a faculty member at the University of Texas Southwestern Medical Center. He earned his PhD at the University of California Davis, where his interests in small molecule NMR began by studying the natural products chemistry of marine organisms. He did his postdoctoral work at the Scripps Institution of Oceanography in San Diego with microbial natural products. His research focuses on the chemical and biological characterization of natural products with therapeutic potential in the areas of oncology and infectious disease.