Principles of Toxicology Testing

ISBN-13: 9781138457065 / Angielski / Twarda / 2017

Frank A. Barile

Opis

Suitable for budding toxicologists worldwide, this book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development.

Spis treści

Basic Concepts in Toxicology Testing. Introduction to Principles of Toxicology Testing. Effects of Chemicals. Toxicokinetics. Risk Assessment and Regulatory Toxicology. Descriptive Animal Toxicology Tests. Toxicology Testing in Vivo. Acute Toxicology Testing. Subchronic and Chronic Toxicology Testing. Acute Dermal Toxicology Testing. Acute Ocular Toxicology Testing. Toxicity Testing for Fertility and Reproduction. Carcinogenicity and Mutagenicity Testing in Vivo. Toxicology Testing in Vitro. Introduction to In Vitro Toxicology Testing. Cell Culture Methodology. Cell Culture Methods for Acute Toxicology Testing. Acute Local Toxicology Testing in Vitro. Toxicokinetic Studies in Vitro. Mutagenicity and Carcinogenicity Testing in Vitro. Reproductive and Teratogenicity Studies in Vitro. High Throughput Screening and Microarray (MA) Analysis. Toxicogenomics and Epigentic Testing in Vitro. Experimental Design and Statistics. Applications of Alternative Models for Toxicology Testing.

O autorze

Frank A Barile