Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development: Volume 14

ISBN-13: 9780323884877 / Angielski / Miękka / 2022

Michael B. Hicks; Paul D. Ferguson

Spis treści

1. Application space for SFC in pharmaceutical drug discovery and development
2. Evolution and history of SFC as greener preparative Tool
3. SFC for chiral resolution of pharmaceuticals
4. Advantages of new column technologies with SFC
5. Synthetic and process chemistry reaction screening
6. Method development approaches for small molecule analytes
7. Expanding the boundaries of SFC: starting materials, excipients, lipidated peptide conjugates, PEGs
8. Application driven detection
9. Advantages of SFC - over historical and compendial normal phase methods
10. Peptides, proteins and the use of water with SFC methods
11. Other miscellaneous applications of SFC as a sustainable analytical tool, nucleic acids and sugars