Plant-Derived Bioactives: Chemistry and Mode of Action

ISBN-13: 9789811523632 / Angielski / Miękka / 2021 / 589 str.

Mallappa Kumara Swamy

Spis treści

Chapter 1. Orientin, a C-Glycosyl Flavonoid Mitigates Colorectal Cancer.- Chapter 2. Plant Flavonoids against Colorectal Cancer and Mechanisms of Action.- Chapter 3. Plant Neoflavonoids: Chemical Structures and Biological functions.- Chapter 4. Polyphenols Role in Autoimmune and Chronic Inflammatory Diseases and the Advent of Computer-driven Plant Therapies.- Chapter 5. Plant Alkaloids: Structures and Bioactive Properties.- Chapter 6. Pelargonidin, a Dietary Anthocyanidin in the Prevention of Colorectal Cancer and its Chemoprotective Mechanisms.- Chapter 7. Targeting the Key Signaling Pathways in Breast Cancer Treatment using Natural Agents.- Chapter 8. Chromenes: Phytomolecules with Immense Therapeutic Potential.- Chapter 9. Coumarins: An Important Phytochemical with Therapeutic Potential.- Chapter 10. Pomegranate Peel and Its Anticancer Activity: A Mechanism-Based Review.- Chapter 11. Lycopene: Chemistry, Biosynthesis, Health Benefits and Nutraceutical Applications.- Chapter 12. Dietary Agents in the Prevention of Cataractogenesis: Results from Preclinical Observations.- Chapter 13. Bioactive Xanthones from Garcinia mangostana.- Chapter 14. Capsaicin and its Potential Anticancer Mechanisms of Actions.- Chapter 15. Biosynthesis, Genetic Regulation and Therapeutic Potential of Capsaicinoids.- Chapter 16. Phytochemicals in the Prevention and Cure of Cancers.- Chapter 17. Anticancer and Chemopreventive Phytochemicals from Cruciferous Plants.- Chapter 18. Pharmacological Properties of Essential Oil Constituents and their Mechanism of Actions.- Chapter 19. Neuroprotective Compounds from Plant Sources and their Mode of Action: An Update.- Chapter 20. Oroxylum indicum Vent. and its Bioactive Compound, Baicalein against Cancer Cells: Mechanisms of Action. Chapter 21. Indian tropical fruits and their bio-active compounds against human diseases.- Chapter 22. Citrus Flavanoids in Preventing Cardiovascular Diseases.- Chapter 23. Bioflavonoids as Promising Antiosteoporotic Agents.- Chapter 24. Computational Approaches in Drug Development and Phytocompounds Analysis.- Chapter 25. Computational Methods Used in Phytocompounds-based Drug Discovery.- Chapter 26. In silico molecular docking of glycyrrhizin and breast cancer cell line proteins.

O autorze

Dr. Mallappa Kumara Swamy is a Professor at the Department of Biotechnology at East West First Grade College (Affiliated to Bangalore University), Bengaluru, India. He pursued his postdoctoral research at the Department of Crop Science, Faculty of Agriculture, Universiti Putra Malaysia (UPM), Serdang, Malaysia from 2014 to 2018. Before that, he worked as an Associate Professor and Head of the Department of Biotechnology at Padmashree Institute of Management and Sciences, Bangalore University, Bengaluru, India. He obtained his PhD (Biotechnology) from Acharya Nagarjuna University, Guntur, India in 2013. He has more than 16 years of teaching and research experience in the fields of plant biotechnology, secondary metabolites production, phytochemistry and bioactive studies, and he has published more than 100 research papers in peer-reviewed journals and 25 book chapters. He has edited 10 books with Springer Nature Singapore Pte Ltd., CRC Press (Taylor & Francis Group), USA, and Studium Press, India. He is also an editorial board member and reviewer for various high- impact international journals. He currently works in the area of natural product research, plant cell and tissue culture technology for bioactive compounds production and evaluation of their bioactivities. His research also focuses on nanobiotechnology for medical applications.

Blurb

Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. 

This book is divided into 2 volumes and offers detailed information on plant-derived bioactive compounds, including recent research findings. Volume 1, “Plant-derived Bioactives: Chemistry and Mode of Action” discusses the chemistry of highly valued plant bioactive compounds and their mode of actions at the molecular level. Volume 2, “Plant-derived Bioactives: Production, Properties and Therapeutic Applications” explores the sources, biosynthesis, production, biological properties and therapeutic applications of plant bioactives.

Given their scope, these books are valuable resources for members of the scientific community wishing to further explore various medicinal plants and the therapeutic applications of their bioactive compounds. They appeal to scholars, teachers and scientists involved in plant product research, and facilitate the development of new drugs.