Phytochemicals as Lead Compounds for New Drug Discovery

ISBN-13: 9780128178904 / Angielski / Miękka / 2019 / 378 str.

Chukwuebuka Egbuna; Shashank Kumar; Jonathan C. Ifemeje

Spis treści

Part I: Plants As Natural Sources Of Drugs 1. Plant Secondary Metabolites as Lead Compounds for the Production of Potent Drugs 2. Factors Affecting the Choice for Plant-based Products in Drug Discoveries 3. Advances in Computer-Aided Drug Discovery 4. FDA drug candidacy acceptance criteria and steps: Problems and way forward

Part II: Bio-functional Leads for Drug Development 5. Bioactive lead compounds and molecular targets for the treatment of heart diseases 6. Natural bioactive lead compounds effective against haematological malignancies 7. Adjunct Therapeutic Potential of Phytochemicals Against Cancer 8. Anti-diabetic lead compounds and targets for drug development 9. Anti-obesity functional leads and targets for drug development 10. Phytochemicals as therapeutic interventions in neurodegenerative diseases 11. Organosulfur phytochemicals against metabolic and neurodegenerative diseases: Benefits and risks 12. Lead compounds with the potentials for the treatment of chronic liver diseases 13. Phytocompounds and potential target sites against skin diseases 14. Phytochemicals as emerging therapeutic agents for alopecia treatment 15. Antiviral phytocompounds for drug development: A data mining studies 16. Shikimic acid as intermediary model for the production of drugs effective against influenza virus 17. Antimicrobial Lead Compounds from Marine Plants 18. Antibacterial lead compounds and targets for drug development 19. Awareness and Current Therapeutic Strategies of Malaria 20. Bioactive lead compounds and targets for the development of anti-malarial drugs 21. Bioactive lead compounds and targets for the development of anti-inflammatory drugs 22. Functional lead compounds and targets for the development of drugs for the treatment of male infertility 23. Prenylated flavonoids as a promising drug discovery candidate: A pharmacological update