Phytochemicals: Nutrient-Gene Interactions

ISBN-13: 9780367391119 / Angielski / Miękka / 2019 / 232 str.

Mark S. Meskin; Wayne R. Bidlack; R. Keith Randolph

Opis

This book analyzes the mechanisms of action and impact of phytochemical-gene interactions on health, aging, and disease. It covers experimental methodologies for identifying significant interactions between diet, genetic variants, and different markers of cardiovascular disease, inflammation, and obesity. It examines the role of resveratrol in cardiovascular health; the preventative mechanisms of whole grains and omega-3 fatty acids; epidemiological research on plant-based foods; the non-antioxidant cellular properties of vitamin E; and controlled clinical trials. It also explores the role of nutrigenomics in developing safe and effective phytochemical products.

Spis treści

Nutrigenomics: Opportunities and Challenges. Gene–Diet Interactions, Blood Lipids, and Cardiovascular Disease Risk: The Rise of Nutrigenetics. Diet–Disease Interactions at the Molecular Level: An Experimental Paradigm. Anti-Inflammatory Phytochemicals: In Vitro and Ex Vivo Evaluation. Lipid Peroxidation, Gene Expression, and Resveratrol: Implications in Atherosclerosis. Adipose Tissue Gene Expression in the Context of Inflammation and Obesity. Gene–Environment Interactions in Obesity: Implications for the Prevention and Treatment of Obesity. Saturated Fat Consumption in Ancestral Human Diets: Implications for Contemporary Intakes. Plant-Based Diets and Prevention of Cardiovascular Disease: Epidemiologic Evidence. Evolutionary Aspects of Diet, the Omega-6/Omega-3 Ratio, and Gene Expression. Beyond Fiber: Whole Grains and Health. Molecular Activities of Vitamin E.

O autorze

Mark S. Meskin, Wayne R. Bidlack, R. Keith Randolph