Nutrients and Epigenetics

ISBN-13: 9781420063547 / Angielski / Twarda / 2009 / 258 str.

Sang-Woon Choi; Simonetta Friso

Opis

Epigenetics is a relatively new area for understanding many of the disease processes involved with mediated changes in gene expression in response to dietary and other lifestyle exposures. Presenting up-to-date research on the relationship between nutrition and the cutting-edge field of epigenetics, this book takes a close look at the impact of epigenetics on aging, embryonic growth, and the development of cancer. With the aid of numerous color illustrations and photographs, it effectively describes how nutrients modulate physiologic and pathologic processes through the modulation of epigenetic phenomena. With internationally respected contributors, this book is an essential guide to this largely unchartered field.

Spis treści

Introduction. Methylation on the nucleosome. Mammalian DNA methyltransferases. Chromatin remodeling and histone modifications. Nutrients and DNA methylation. Nutrients, histone modifications, and chromatin remodeling in chronic inflammation. Nutrients, epigenetics, and embryonic development. Nutrition, epigenetics, and aging. Nutrition, epigenetics, and cancer. Conclusions and future perspectives.

O autorze

Sang-Woon Choi, MD, PhD, Tufts University, Boston, Massachusetts, USA

Simonetta Friso, MD, PhD, University of Verona, Italy