Nuclear Envelope Dynamics in Embryos and Somatic Cells

ISBN-13: 9781461349372 / Angielski / Miękka / 2012 / 174 str.

Philippe Collas

Opis

This volume provides an exhaustive review of the most current knowledge of the composition, architecture and dynamics of the nuclear envelope. In contrast to other comprehensive works on cellular membranes in general, this book is the first to specifically address the nuclear envelope. Experts in the field relate the different domains of the nuclear envelope, their biogenesis, their composition, their mode of targeting to chromosomes and how they dissociate from chromosomes upon cell division. A wealth of information from several experimental systems is provided, such as dividing somatic cells, embryos and nuclear assembly assays in cell-free extracts, in a wide range of vertebrate and invertebrate organisms ranging from humans to yeast. The book also contains up-to-date reviews on the relationship between mutations in proteins of the nuclear envelope and Emery-Dreifuss muscular dystrophy. The breadth of topics covered in what may seem to be a field as narrow as the nuclear envelope makes this volume a valuable reference.

Spis treści

Preface. 1. Dynamics of the Vertebrate Nuclear Envelope; M. Mansharamani, et al. 2. Dynamics of Nuclear Envelope Proteins During the Cell Cycle in Mammalian Cells; J. Ellenberg. 3. Targeting and Retention of Proteins in the Inner and Pore Membranes of the Nuclear Envelope; C. Östlund, et al. 4. Dynamic Connections of Nuclear Envelope Proteins to Chromatin and the Nuclear Matrix; R. Foisner. 5. Role of Ran GTPase in Nuclear Envelope Assembly; C. Zhang, P.R. Clarke. 6. Mitotic Control of Nuclear Pore Complex Assembly; K. Bodoor, B. Burke. 7. Structure, Function and Biogenesis of the Nuclear Envelope in the Yeast Saccharomyces cerevisiae; G. Simos. 8. Nuclear Envelope Breakdown and Reassembly in C. elegans: Evolutionary Aspects of Lamina Structure and Function; Y.B. Tzur, Y. Gruenbaum. 9. Nuclear Envelope Assembly in Gametes and Pronuclei; D. Poccia, et al. 10. Nuclear Envelope Dynamics in Drosophila Pronuclear Formation and in Embryos; M.F. Wolfner. 11. The Distribution of Emerin and Lamins in X-Linked Emery-Dreifus Muscular Dystrophy; G.E. Morris, et al. 12. Laminopathies: One Gene, Two Proteins, Five Diseases; C. Vigouroux, G. Bonne. Index.