Novel s-Triazinyl Thioureas via Cu Catalyzed Coupling Reactions

ISBN-13: 9783659871276 / Angielski / Miękka / 2016 / 92 str.

Harshad Lakum; Dhruvin Shah; Kishor Chikhalia

Opis

This book describes the synthesis of some novel s-triazinyl thiourea congeners endowed with various aromatic amine as well as piperazine motifs via an efficient and sustainable copper catalyzed coupling. Development of optimized method for the synthesis of many heterocyclic moieties is still a challenge. We have developed an efficient technique to synthesize thiourea derivatives using Copper as catalyst in order to prepare effective antimicrobial agents. All the newly prepared scaffolds were fully characterized and evaluated for their in vitro antibacterial, antifungal as well as anti-TB activity.

O autorze

Dr. Harshad P. Lakum has completed Ph.D. in the field of Synthetic Medicinal Chemistry from Gujarat University, India. He has published many research articles in international journals and also presented in conferences. He is actively involved in the design, synthesis and studies of novel bioactive heterocycles.