Nanomedicine: Design and Applications of Magnetic Nanomaterials, Nanosensors and Nanosystems

ISBN-13: 9780470033517 / Angielski / Twarda / 2008 / 484 str.

Vijay K. Varadan; Lin-Feng Chen

Opis

Recent advances in nanomedicine offer ground-breaking methods for the prevention, diagnosis and treatment of some fatal diseases. Amongst the most promising nanomaterials being developed are magnetic nanomaterials, including magnetic nanoparticles and magnetic nanosensors. Some nanomagnetic medical applications are already commercially available with more set to be released over the coming years.

"Nanomedicine, Design and Applications of Magnetic Nanomaterials, Nanosensors and Nanosystems" presents a comprehensive overview of the biomedical applications of various types of functional magnetic materials. The book provides an introduction to magnetic nanomaterials before systematically discussing the individual materials, their physical and chemical principles, fabrication techniques and biomedical applications. This methodical approach allows this book to be used both as a textbook for beginners to the subject and as a convenient reference for professionals in the field.Discusses magnetic nanoparticles including nanowires, nanotubes, zero-dimensional nanosperes and naturally existing magnetosomes.Examines intrinsically smart magnetic materials and describes their part in the development of biomedical sensors and biochips, which are often used in biomedical tests.Integrates the research efforts of different disciplines - from materials sciences to biology and electrical engineering to medicine - in order to provide a unified and authoritative guide to a richly interdisciplinary field.

This volume is of great appeal to students and researchers in the fields of electrical and electronic engineering, biomedical engineering, nanotechnology, materials science, physics, medicine and biology. It is also of interest to practising engineers, materials scientists, chemists and research medical doctors involved in the development of magnetic materials and structures for biomedical applications.

Spis treści

CONTENTS

Preface

About the Authors Introduction

1.1 What is nanoscience and nanotechnology

1.2 Magnets and nanometers: mutual attraction

1.3 Typical magnetic nanomaterials

1.4 Nanomedicine and magnetic nanomedicine

1.5 Typical biomedical applications of functional magnetic nanomaterials

Physical background for the biomedical applications of functional magnetic nanomaterials

2.1 Requirements for biomedical applications

2.2 Fundamentals of nanomagnetism

2.3 Magnetic relaxation of ferrofluids

2.4 Magnetorheology of ferrofluids

2.5 Manipulation of magnetic particles in fluids

2.6 Interactions between biological nanomaterials and functionalized magnetic nanoparticles

Magnetic nanoparticles

3.1 Introduction

3.2 Basics of nanomagnetics

3.3 Synthesis techniques

3.4 Synthesis of magnetic nanoparticles

3.5 Bio–inspired magnetic nanoparticles

3.6 Functionalization of magnetic nanoparticles

3.7 Future prospects

Biomedical applications of magnetic nanoparticles

4.1 Introduction

4.2 Diagnostic applications

4.3 Therapeutic applications

4.4 Physiological aspects

4.5 Toxic effects

Magnetosomes and their biomedical applications

5.1 Introduction

5.2 Magnetosome formation

5.3 Cultivation of magnetotactic bacteria

5.4 Characterization of magnetosomes

5.5 Biomedical applications of magnetosomes

Magnetic nanowires and their biomedical applications

6.1 Introduction

6.2 Magnetism of magnetic nanowires

6.3 Template–based synthesis of magnetic nanowires

6.4 Characterization of magnetic nanowires

6.5 Functionalization of magnetic nanowires

6.6 Magnetic nanowires in suspension

6.7 Biomedical applications of magnetic nanowires

Magnetic nanotubes and their biomedical applications

7.1 Introduction

7.2 Magnetism of nanotubes

7.3 Multifunctionality of magnetic nanotubes

7.4 Synthesis and characterization of magnetic nanotubes

7.5 Biomedical applications of magnetic nanotubes

Magnetic biosensors

8.1 Introduction

8.2 Magnetoresistance–based sensors

8.3 Hall effect sensors

8.4 Other sensors detecting stray magnetic fields

8.5 Sensors detecting magnetic relaxations

8.6 Sensors detecting ferrofluid susceptibility

Magnetic biochips: basic principles

9.1 Introduction

9.2 Biochips based on giant magnetoresistance sensors

9.3 Biochips based on spin valve sensors

9.4 Biochips based on magnetic tunnel junctions

9.5 Fully integrated biochips

Biomedical applications of magnetic biosensors and biochips

10.1 Introduction

10.2 DNA analysis

10.3 Protein analysis and protein biochips

10.4 Virus detection and cell analysis

10.5 Study of the interactions between biomolecules

10.6 Detection of biological warfare agents

10.7 Environmental monitoring and cleanup

10.8 Outlook

Appendix

A1. Units for magnetic properties