Modelling Metabolism with Mathematica

ISBN-13: 9780367395223 / Angielski / Miękka / 2019 / 328 str.

Peter Mulquiney; Philip W. Kuchel

Opis

Using the human erythrocyte as an example, this book presents the approaches, methods, tools, and algorithms for modelling the chemical-dynamics of metabolic pathways. The authors explain the concepts underpinning the deterministic theory of chemical and enzyme kinetics in such a way that readers will be able to formulate their own models of time-dependent metabolic systems. They present a graded series of computer models of metabolic pathways leading up to that of human erythrocyte metabolism, and they document a consistent set of rate equations and associated kinetic parameters relevant to the human erythrocyte, which makes the book of particular interest to readers involved with red cell enzymology.

Spis treści

Introduction to Chemical Kinetics and Numerical Integration. Elements of Enzyme Kinetics. Basic Procedures for Simulating Metabolic Systems. Advanced Simulation of Metabolic Pathways. Metabolic Control Analysis. Parameter Estimation. Model of Red Cell Metabolism. Metabolic Control Analysis of Human Erythrocyte Metabolism. Appendices.

O autorze

Mulquiney, Peter; Kuchel, Philip W.