Microwave assisted synthesis and antimicrobial evaluation : of thiophenyl thiazole depended quinoxaline derivatives

ISBN-13: 9786139905171 / Angielski / Miękka / 2018 / 84 str.

Haresh Kathrotiya; Yogita Chovatiya

Opis

Heterocyclic compounds represent an important class of biological active molecules. Specifically those containing quinoxaline derivatives have evoked considerable attention in recent years as these are endowed. Quinoxalines are a versatile class of nitrogen containing heterocyclic compounds and they constitute useful intermediates in organic synthesis. Quinoxaline, also called a benzopyrazine, in organic chemistry, is a heterocyclic compound containing a ring complex made up of a benzene ring and a pyrazine ring and they are isomeric with cinnolenes, phthalazines and quinazolines. There are a number of processes available to generate quinoxaline but generally, they are synthesized by the condensation of 1, 2-dicarbonyls with 1,2 diamines in presence of suitable catalyst using various solvent systems. They possess well known biological activities including AMPA/GlyN receptor antagonis, antihistaminic agents, anti-trypanosomal activity, anti-herps, antiplasmodial activity, Ca uptake/ Release inhibitor, inhibit vascular smooth muscle cell proliferation.

O autorze

Kathrotiya, Haresh
Dr. Haresh kathrotiya, Department of chemistry, Saurashtra University, Rajkot - 360005.