Methods of Non-A-Amino Acid Synthesis

ISBN-13: 9780367379346 / Angielski / Miękka / 2019 / 242 str.

Michael Bryant Smith

Opis

This book has been extensively rewritten and reorganized, providing an up-to-date review of strategies and methods for non-α-amino acid synthesis, particularly those amino acids that are key synthetic intermediates or important compounds in their own right. The new edition contains many updated references and has a greater emphasis on the biological importance of non-α-amino acids. In addition to an array of synthetic methods, the book offers discussions on why non-α-amino acids are important. It discusses conversion of cyclic precursors, conjugate addition reactions, stereoselectivity, and more.

Spis treści

Functional Group Exchanges. Cyclic Precursors. Conjugate Addition Reactions. Enolate Anion and Related Reactions. Diastereoselective and Enantioselective Syntheses. Biologically Important Amino Acids. Aminocyclic and Heterocyclic Amino Acids. Index.

O autorze

Michael B. Smith attended Purdue University, graduating with a Ph.D. in Organic Chemistry. His postdoctoral work took place at the Arizona State University with George R. Pettit and at the Massachusetts Institute of Technology with Sidney Hecht. Dr. Smith joined the faculty at the University of Connecticut in 1977, where he now holds the rank of full professor. He is the author of the 5th–7th editions of March's Advanced Organic Chemistry, Organic Synthesis (3rd edition), and Organic Chemistry: An Acid-Base Approach.