Membrane Biogenesis

ISBN-13: 9783642731860 / Angielski / Miękka / 2011 / 477 str.

Jos A. F. Op Den Kamp

Opis

This book provides a coherent overview of the various aspects of membrane biogenesis, considering the major constituents - phospholipids and glycoproteins - in a balanced way. New perspectives in the dynamics of the assembly of biomembranes are discussed and followed by detailed contributions on methodological approaches. Also included are short reviews on protein translocation and sorting across different membranes.

Spis treści

Techniques to determine transbilayer organization and dynamics of membrane phospholipids..- Transbilayer organization and mobility of phospholipids in normal and pathologic erythrocytes..- Lipid localization and mobility in the plasmalemma of the aortic endothelial cells are reversibly affected by the presence of cell junctions..- Phospholipid dynamics in membrane biogenesis in hepatocytes..- The regulation of phosphatidylcholine synthesis at the subcellular level in Krebs II ascite cells..- Phospholipid asymmetry during erythropoiesis..- Factors which may alter the assembly of biomembranes so as to influence their structure or function..- Myocardial cell death and the possible role of sarcolemmal phospholipids (based on morphological observations)..- The role of mitochondrial membrane phospholipid polar headgroups in yeast cytochrome c oxidase kinetics..- The regulation of bilayer stability in bacteria..- Membrane structure and dynamics by NMR. Part I: effect of cyclopropane ring, double bonds and sterols on the structure and dynamics of phospholipid membranes..- Membrane structure and dynamics by NMR. Part II: the action of polyene antibiotics and toxins on biological membranes.- Interaction of the bibenzimidazole derivative Hoechst 33258 with lipid bilayers - a fluorescence study..- Physical membranes : a short review..- Anchoring of membrane proteins by glycosyl-phosphatidylinositol..- Fatty acylation of proteins..- Interaction of the mitochondrial precursor protein apocytochrome c with modelmembranes and its implications for protein translocation..- The LDL receptor: structural insight from human mutations..- The assembly and transfer of oligosaccharide chains to proteins..- Sequence determinants of protein sorting into and across membranes..- Components involved in protein translocation across the membrane of the endoplasmic reticulum..- Import of small secretory and plasma membrane proteins into the endoplasmic reticulum..- Biogenesis and membrane topology of outer membrane proteins in Escherichia coli..- What can we learn from colicins about the dynamics of insertion and transfer of proteins into and across membranes..- Bacterial protein translocation..- The use of hybrid proteins in the study of protein targeting signals..- Pullulanase: a new specific secretion pathway in Escherichia coli..- A genetic analysis of pullulanase export from Klebsiella aerogenes..- Cloning of xcp genes possibly involved in protein secretion in Pseudomonas aeruginosa..- Vacuole division and inheritance in Saccharomyces cerevisiae..- The lactose carrier of E.coli:: protease dependent in vivo inactivation..