Melatonin in the Promotion of Health

ISBN-13: 9781439839799 / Angielski / Twarda / 2011 / 584 str.

Ronald Ross Watson

Opis

This new edition presents information on how melatonin is synthesized and produced in the body as well as how this hormone affects several diseases. The book heavily focuses on prevention as well as treatment of various human disease states including behavior disorders, mental disorders, breast cancer, bone health, and gastrointestinal diseases. It covers the role of melatonin in the prevention of oxidative stress, mutagenesis, sun damage, ocular health, gut motility, and detoxification. It also presents mechanisms of melatonin action in humans including cell modulation, signaling mechanisms, protective effects, and melatonin receptors as well as its role as an antioxidant.

Spis treści

Melatonin Time Line: From Discovery to Therapy. Melatonin and Circadian Rhythms: An Overview. Synthesis and Metabolism of Melatonin in the Skin and Retinal Pigment Epithelium. Melatonin in Prevention of Mutagenesis, Oxidation, and Other Damage to Cells. Cardiovascular Protection by Melatonin. Melatonin Effect on Reproduction. Melatonin and the Prevention of Ultraviolet Solar Skin Damage. Melatonin and Type 2 Diabetes. Melatonin, Sleep, and Immune Modulation: Role in Health and Disease.Melatonin as a Treatment for Uveitis. Role of Melatonin in Regulating Gut Motility. Melatonin and Food Safety: Investigating a Possible Role in the Seasonality of the Bacterial Pathogen Escherichia coli O157:H7 in Cattle. Melatonin in Dentistry. Melatonin as a Potential Treatment of Gastrointestinal Diseases. The Uses of Melatonin in Anesthesia and Surgery. Melatonin in Bone Health. Prevention and Treatment of Breast Cancer Using Melatonin. Molecular and Epigenetic Effects of Melatonin in Breast Cancer. Melatonin in Mental Disorders: Treatment and Prevention. Melatonin in Control of Gastric Secretion and Prevention of Gastric Mucosal Lesions. Melatonin for the Control of Reproduction in Small Ruminants. Melatonin in the Pancreatic Protection and Modulation of Pancreatic Exocrine Secretion. Life Environment and Sleep: Melatonin Production Affected by Light and Ambient Temperature in Humans. Decreased Light Transmittance Because of Aging and Melatonin. Melatonin and Treatment of Disorders Related to Jet Lag and Shift Work. Melatonin and Its Byproducts on Age-Related Macular Degeneration. Melatonin and Melanoma. Melatonin and Inflammation—The Role of the Immune–Pineal Axis and the Sympathetic Tonus. Neuroendocrinological Effects of Antidepressants: Is There a Role for Melatonin? Role of Melatonin in Collagen Synthesis. Melatonin and DNA Protection. Melatonin Modulation of Vascular Structure and Function. Melatonin and Sleep Disturbances in Patients with End-Stage Renal Disease. Melatonin and Traumatic Stress. Measurement of Melatonin in Other Body Fluids. Cell Studies with Melatonin Exposed to UV Light and Ionizing Radiation. Melatonin and Oxidation.