Mammalian Transient Receptor Potential (Trp) Cation Channels: Volume I

ISBN-13: 9783662512234 / Angielski / Miękka / 2016 / 726 str.

Bernd Nilius; Veit Flockerzi

Opis

This book offers up-to-date information on the molecular and functional properties and pharmacology of mammalian Transient Receptor Potential channels, from close-up views of single protein/channels to broader principles of function and important pathologies.

Spis treści

TRPs -Truly Remarkable Proteins.- The TRCP Subfamily: TRPC1.- TRPC2.- TRPC3- a Multifunctional Signaling Molecule.- TRPC4 and TRPC4-Containing Channels.- TRPC5.- TRPC6: Physiological Function and Pathophysiological Relevance.- Transient Receptor Potential Canonical 7 (TRPC7).- The TRPV Subfamily: TRPV1.- TRPV2.- TRPV3.- The TRPV4 Channel.- TRPV5, a Ca2+ Channel for the Fine Tuning of Ca2+ Reabsorption.- TRPV6 Channels.- The TRPM Subfamily: TRPM1.- TRPM2.- TRPM3.-TRPM4.- TRPM5.- TRPM6.- TRPM7.- TRPM8.- The TRPA1, TRPML and TRPP Subfamily: TRPA1.- TRPML1: An Ion Channel in the Lysosome.- TRPML2 and Mucolipin Evolution.- TRPML3.- TRPP Subfamily and Polycystin-1 Proteins.