Malignant Melanoma: Biology, Diagnosis, and Therapy

ISBN-13: 9781461289838 / Angielski / Miękka / 2011 / 202 str.

Larry Nathanson

Opis

Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Un fortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions such as lung can cer, genitourinary cancer, pediatric oncology, etc.; second, by asking emi nent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more."

Spis treści

I. Basic Biology and Immunology.- 1. Characteristics of cultured human melanocytes from different stages of tumor progression.- 2. Gangliosides as antigens of human melanoma.- II. Molecular genetics.- 3. The cytogenetics of human malignant melanoma and premalignant lesions.- 4. The ha-ras-1 oncogene and the molecular genetics of human melanoma.- III. Epidemiology.- 5. Epidemiologic aspects of intraocular malignant melanoma.- 6. Abnormal nevi, excess total nevi, and melanoma: an epidemiologic perspective.- IV. Diagnosis and Prognosis.- 7. Fine needle aspiration biopsy of metastatic melanoma.- 8. Radioimmunoimaging of malignant melanoma with monoclonal antibodies.- 9. Flow cytometry in melanoma.- V. Therapy.- 10. Randomized trials of heated perfusion of extremity melanoma.- 11. Vaccinia virus oncolysates in the treatment of malignant melanoma.- Appendix to Chapter 6.