Knowledge Discovery in Proteomics

ISBN-13: 9780367392178 / Angielski / Miękka / 2019 / 360 str.

Igor Jurisica; Dennis Wigle

Opis

A timely, authoritative discussion of some of the key issues in high throughput proteomics, Knowledge Discovery in Proteomics provides examples of some of the major challenges of knowledge discovery in the field. The authors focus mass spectrometry-based protein analysis, protein-protein interaction network analysis, high-throughput protein crystallization, systematic, integrated analysis of multiple data repositories, and systems biology. For each area they describe the challenges posed by the type of data produced and present potential solutions. Taking a systems approach, they cover individual data and integrate its computational aspects, from data preprocessing to integration.

Spis treści

Introduction. Knowledge Management. Current Status and Future Perspectives of Mass Spectrometry. Graph Theory Analysis of Protein--Protein Interactions. HTP Protein Crystallization Approaches. Integration of Diverse Data, Algorithms, and Domains. From High-Throughput to Systems Biology. References.

O autorze

Jurisica, Igor; Wigle, Dennis