Isolation and Characterization of Alkaloids from Carica Papaya Linn

ISBN-13: 9786205520352 / Angielski / Miękka / 76 str.

Aishwarya Shinde; Dinesh Hase

Opis

The carpaine was isolated from Carica papaya L. leaf, was identified by means of Fourier transform infrared spectroscopy, mass spectrometry, nuclear magnetic resonance, HPLC and was determined by LCMS, The powder of dried leaves was macerated and extracted with Methanol/water/HCl (89:10:1 V/V/V) to produce crude alkaloid. The extract was fractionated on a silica gel column chromatography using methanol/chloroform (5:95 v/v) as the eluate. The major fraction was isolated according to Rf values of thin-layer chromatography (TLC) (silica gel, methanol/chloroform [15:85 v/v]) exposed by Dragendroff's reagent. The extraction procedure, sample preparation, and LCMS conditions were evaluated and optimized. The study was done on pharmacological studies on leaves of Carica Papaya Linn.

O autorze

Aishwarya Shinde-Shete holds a B. of Pharm from Sanjivani College of Pharmacy, Kopargaon and a Masters from Amrutvahini College of Pharmacy Sangamner Maharashtra. The author is currently pursuing a PhD at Poona University. Author of over 20 papers published in national and international reputed journals. Holds a Young researcher Award 2021 by InSc.