Iodine-DMSO catalyzed Chemoselective aromatization of THBC

ISBN-13: 9786202553438 / Angielski / Miękka / 2020 / 160 str.

Sunil Vitthalrao Gaikwad; Pradeep Lokhande; Milind V. Gaikwad

Opis

This book deals with novel methodology for chemoselective dehydrogenation, aromatization, deallyalation, No deallylation with molecular iodine in DMSO and their utility is extended to the synthesis of beta-carboline alkaloids and biologically active beta-carboline and indazole heterocycles. Aromatic-beta-carboline alkaloids are composed of nitrogen-containing heterocycles and represent a tricyclic pyrido[3,4-b]indole ring system.1 They are present in a large number of natural products like marine sponges and territorial plants2 as well as in as normal constituents of human tissues and body fluids3. The beta-carboline moiety is a very important synthetic intermediate for a variety of pharmaceutically important natural products and drug molecules.

O autorze

Gaikwad, Sunil Vitthalrao
Dr.SUNIL V. GAIKWAD ( MSc. Ph.D., Department of Chemistry, savitribai Phule Pune University)Research AssociateCSIR-National Chemical Laboratory, Pune Erasmus Mundus fellow at Santiago de Compostela Spain ( 2015-2017).