Investigative Immunotoxicology

ISBN-13: 9780367393298 / Angielski / Miękka / 2019 / 484 str.

Helen Tryphonas; Michel Fournier; Barry R. Blakley

Opis

Reflecting key advances, Investigative Immunotoxicology evaluates proposed experimental animal models and approaches, and discusses the contribution that immunotoxicity makes in assessing chemical-induced adverse health effects. After reviewing general concepts, the book discusses emerging methodologies at the cellular and molecular levels, and describes advances in animal model development in testing food allergenicity and genetically modified products. It presents animal models of autoimmunity associated with chemical exposure, includes recommendations for selecting sentinel species in ecotoxicology, and concludes with a review of immunotoxicology as it relates to a variety of wildlife species.

Spis treści

The Immune System. Approaches and Models Relevant to the Assessment of Chemical-Induced Immunotoxic Effects in the Ecosystem. Approaches and Models Relevant to the Assessment of the Impact of Chemical-Induced Immunotoxicity on Human Health. Models and Approaches to Chemical-Induced Allergenicity. Autoimmunity. Emerging Issues in Immunotoxicology. The Role of Immunotoxicology in Risk Assessment and the Regulatory Process.

O autorze

Helen Tryphonas, Michel Fournier, Barry R. Blakley, Judit E. G.Smits, Pauline Brousseau