In Situ Bioavailability and Toxicity of Organic Chemicals in Aquatic Systems

ISBN-13: 9781071623558 / Angielski / Miękka / 2023

Opis

This detailed volume examines the complex study of the assessment of in situ bioavailability and toxicity of organic chemicals in aquatic systems with a toolbox of reliable techniques. Beginning with a section on approaches for chemical analytical and bioanalytical techniques in bioavailability research, the book continues with methods to monitor effects in situ and conduct bioassays to assess the effects of complex environmental samples. It concludes with descriptions of various computational models. Written for the Methods in Pharmacology and Toxicology series, chapters feature the kind of expert implementation advice that leads to greater success in the field. 

Authoritative and versatile, In Situ Bioavailability and Toxicity of Organic Chemicals in Aquatic Systems serves as an ideal guide to aid in tackling the challenge of analyzing and understanding chemical pollution in aquatic systems.

Spis treści

Part I: Chemical Analytical and Bioanalytical Techniques in Bioavailability Research: Passive Sampling/Dosing and Bioaccumulation Assessments

 

1. Equilibrium Sampling of Hydrophobic Organic Contaminants in Sediments

            Gesine Witt, Julia Bachtin, and Sabine Schäfer

 

2. Passive Sampling of Waterborne Contaminants

            Branislav Vrana, Foppe Smedes, and Klára Hilscherová

 

3. Using Tenax Extractable Concentrations to Determine the Bioavailable Contaminant Fraction in Sediments

            Amanda D. Harwood and Samuel A. Nutile

 

4. Quantifying Bioaccumulation in the Aquatic Environment

            Katrine Borgå and Anders Ruus

 

Part II: Monitoring of Effects In Situ and Bioassays to Assess the Effects of Complex Environmental Samples

 

5. In Situ Determination of Genotoxic Effects in Fish Erythrocytes Using Comet and Micronucleus Assays

            Paula Suares Rocha, Björn Deutschmann, and Henner Hollert

 

6. Assessing Adverse Effects of Legacy and Emerging Contaminants in Fish Using Biomarker Analysis and Histopathology in Active Monitoring Scenarios

            Amaia Orbea, Eider Bilbao, and Miren P. Cajaraville

 

7. In Situ Exposure of Aquatic Invertebrates to Detect the Effects of Point and Non-Point Source-Related Chemical Pollution in Aquatic Ecosystems

            Mirco Bundschuh and Ralf Schulz

 

8. Whole Sediment Toxicity Bioassay to Determine Bioavailability and Effects of Aquatic Contaminants Using Zebrafish Embryos

            Sabrina Schiwy, Mirna Velki, and Henner Hollert

 

9. Nematode-Based Effect Assessment in Freshwater Sediments

            Arne Haegerbaeumer, Sebastian Höss, and Walter Traunspurger

 

Part III: Computational Models for Interspecies Comparison and Extrapolation from the Lab to the Field

 

10. In Vitro-In Vivo Extrapolation to Predict Bioaccumulation and Toxicity of Chemicals in Fish Using Physiologically-Based Toxicokinetic Models

            Julita Stadnicka-Michalak and Kristin Schirmer

 

11. Cross-Species Extrapolation Using a Simplifed In Vitro Tissue Explant Assay in Fish

            Bryanna Eisner, Jon Doering, Shawn Beitel, and Markus Hecker

 

12. Extrapolation of Laboratory-Measured Effects to Fish Populations in the Field

            Charles R.E. Hazlerigg