Human Variability in Response to Chemical Exposures Measures, Modeling, and Risk Assessment

ISBN-13: 9780849328053 / Angielski / Twarda / 1998 / 272 str.

David A. Neumann;Anternational Life Sciences Anstitute St;International Life Sciences Institute St

Opis

This work recognizes that an understanding of variability in response is critical in accounting for interindividual variability in susceptibility and, hence, risk, if the regulatory community and others are expected to characterize human health risks associated with exposure to chemicals. Models for incorporating measures of response variability in the risk assessment process are critically reviewed and illustrated with published data.

Spis treści

1. Accounting for Variability in Responsiveness in Human Health Risk Assessment 2. Strategies for Assessing Human Variability in Susceptibility and Using Variability to Infer Human Risks 3. lnterindividual Variability in Neurotoxicity 4. Variability in Human Response to Reproductive and Developmental Toxicity 5. Risk Assessment of the Effects of Ozone Exposure on Respiratory Health: Dealing with Variability in Human Responsiveness to Controlled Exposures 6. Host-Environment Interactions That Affect Variability in Human Cancer Susceptibility 7. Genetic Susceptibility and Cancer Risk 8. Human Variability in Susceptibility and Response: Implications for Risk Assessment

O autorze

Eckerman, David A.