Haschek and Rousseaux's Handbook of Toxicologic Pathology

ISBN-13: 9780124157590 / Angielski / Twarda / 2013 / 3054 str.

Wanda M Haschek

Opis

Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. The 3e has been expanded by a full volume, and covers aspects of safety assessment not discussed in the 2e. Completely revised with many new chapters, it remains the most authoritative reference on toxicologic pathology for scientists and researchers studying and making decisions on drugs, biologics, medical devices and other chemicals, including agrochemicals and environmental contaminants. New topics include safety assessment, the drug life cycle, risk assessment, communication and management, carcinogenicity assessment, pharmacology and pharmacokinetics, biomarkers in toxicologic pathology, quality assurance, peer review, agrochemicals, nanotechnology, food and toxicologic pathology, the environment and toxicologic pathology and more.

• Provides new chapters and in-depth discussion of timely topics in the area of toxicologic pathology and broadens the scope of the audience to include toxicologists and pathologists working in a variety of settings
• Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology
• Features hundreds of full color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations

Recenzje

".the long awaited third edition of this well-respected and essential contributor to toxicological pathology, toxicology and other biological and medical disciplines has been published. It is now presented in three volumes instead of two, and benefits tremendously from having colour illustrations throughout. It is straight forward to read and is laid out in a logical format." --btsNews, June 2014

"..this is the most comprehensive textbook yet published covering the various aspects of toxicological pathology in general, and it does a fair job in covering toxicology topics as well. Its scope and breadth of coverage will find it well placed within any toxicology laboratory and I cannot recommend it more highly. It should take pride of place in the library of any toxicology laboratory and should be an indispensable text for pathologists and toxicologists." --Toxicologic Pathology, January 31, 2014

"Occasionally, a book becomes available that sets a new standard for a subspecialty, and such is the case for the third Edition.This substantially sized.and exceptionally compiled and useful book gathers extensive knowledge from the field of toxicologic pathology as well as tangential and integrative areas.the third edition of this handbook lends itself to being a reference book that reads like an accessible and helpful textbook." --Veterinary Pathology, Vol 51(1), 2014

"The 3 volumes are well organized, and the editors have endeavored to provide clearer and more complete content description for chapter titles that will be easier for nonpathologist to recognize..This.handbook belongs on the physical- or e-shelf of practitioners of toxicologic pathology and toxicology and needs to be in the communal library of a broad range of individuals in life sciences who interact with toxicologic pathologists." --International Journal of Toxicology, December 2, 2013

"The 2 volumes are excellent companions that complement each other as a "1,2" punch! This publication should be on the bookshelf of clinical toxicologists, environmental professionals and laboratory investigators..." --VETERINARY AND HUMAN TOXICOLOGY (October 2002)

"...gives an excellent overview of the numerous processes associated with toxicologic pathology as used in risk assessment. It stands alone as a classic textbook in toxicology, or would be an excellent supplement to other such books. ...Its readability will allow acceptance to all scientists ranging from undergraduate to experienced industry/regulatory professional." --Paul Baldrick for THE BRITISH TOXICOLOGY SOCIETY NEWSLETTER (Spring 2002)

"...very readable, well-referenced, and current... an excellent book for research training." --DOODY'S

Spis treści

Volume 1: Practice of Toxicologic Pathology includes the principles and methods of toxicologic pathology and their application to practice.Volume 2: Safety Assessment and Other Issues in Toxicologic Pathology focuses on toxicologic pathology from a drug discovery and regulatory standpoint, including coverage of data interpretation and expanded content on environmental and food toxicology.Volume 3: Systems Toxicologic Pathology organizes toxicologic pathology by biological systems and addresses the basic structure and function of a particular organ system, its response to toxic injury, mechanisms of injury and methods of evaluation.